Indian Journal of Physical Medicine and Rehabilitation

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VOLUME 31 , ISSUE 4 ( October-December, 2020 ) > List of Articles


Comparative Study of Botulinum Toxin ‘A’ on Upper and Lower Limb Spasticity: A Clinical Aspect

Sanjay K Pandey, Sanyal Kumar, Anjani Kumar, Amit K Mallik

Keywords : Botulinum toxin A, Modified Ashworth scale, Modified Tardieu scale, Range of motion, Spasticity

Citation Information : Pandey SK, Kumar S, Kumar A, Mallik AK. Comparative Study of Botulinum Toxin ‘A’ on Upper and Lower Limb Spasticity: A Clinical Aspect. Indian J Phy Med Rehab 2020; 31 (4):90-95.

DOI: 10.5005/jp-journals-10066-0100

License: CC BY-NC 4.0

Published Online: 17-12-2021

Copyright Statement:  Copyright © 2020; The Author(s).


Aims and objectives: The study intended to compare the effect of botulinum toxin A on clinical aspects of spasticity recorded in various scales. It compared the data of upper and lower limb spasticity. Materials and methods: This is an open-level prospective controlled study, involving patients with upper and lower limb spasticity. Assessment at 3, 12, and 24 weeks post-injections. The modified Ashworth, modified Tardieu scale of spasticity, percentage of passive range motion, Motricity Index for fine and gross motor activity were used. A total of 34 patients were enrolled—25 males, 9 females. There were 51 upper limb and 49 lower limb muscle groups. Three patients were lost after 3 weeks post-baseline follow-up. Results: There was a significant improvement in all the parametric variables post-injections. Aggregate outcome scores comparing groups post-baseline showed a significant difference in modified Tardieu, Motricity Index, interventional goal assessment scales for lower limb muscle groups from upper limb. Conclusion: It was concluded that botulinum toxin A has a definite effect on the impairment and focal disability within a rehabilitation setup of selected patients with focal spasticity.

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