Indian Journal of Physical Medicine and Rehabilitation

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VOLUME 31 , ISSUE 1 ( January-March, 2020 ) > List of Articles

Original Article

Physical Exhaustion Unmasking Underlying Diseases

Mohit Kataruka, Mandeep Saini, Manas R Pattnaik, Kailash Mohitey

Keywords : Gilbert\'s syndrome, G6PD, Physical exhaustion, Thalassemia minor

Citation Information : Kataruka M, Saini M, Pattnaik MR, Mohitey K. Physical Exhaustion Unmasking Underlying Diseases. Indian J Phy Med Rehab 2020; 31 (1):4-7.

DOI: 10.5005/jp-journals-10066-0064

License: CC BY-NC 4.0

Published Online: 24-11-2020

Copyright Statement:  Copyright © 2020; Jaypee Brothers Medical Publishers (P) Ltd.


Physical exhaustion is the temporary physical inability of the muscles to perform optimally. The onset of muscle fatigue during physical activity is gradual and can be reversed by rest and replenishment of electrolyte and hydration. For maximal physical fitness, one should require optimal function of all the body parts and system. It is our humble attempt to find out the underlying disease in patients who presented to us with signs and symptoms of physical exhaustion. Materials and methods: The study was conducted at medical center located at southern part of India from March 2017 to February 2019, and 213 healthy individuals from a physical training institute aged between 18 and 21 was selected, and pre- and post-run blood parameters were measured. Discussion: In our study, more than 20% persons have more than 2-fold rise in blood creatine phosphokinase level which ultimately comes to normal within 48 hours. Eighty-one people among the study population have increase in serum AST/ALT level, and most of them come to normal within 48 hours. Conclusion: For optimal performance and to avoid major catastrophe, it is suggested that before undergoing exhaustive physical exhaustion, one should be properly evaluated.

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