Comparative Study of Botulinum Toxin ‘A’ on Upper and Lower Limb Spasticity: A Clinical Aspect
Sanjay K Pandey, Sanyal Kumar, Anjani Kumar, Amit K Mallik
Botulinum toxin A, Modified Ashworth scale, Modified Tardieu scale, Range of motion, Spasticity
Citation Information :
Pandey SK, Kumar S, Kumar A, Mallik AK. Comparative Study of Botulinum Toxin ‘A’ on Upper and Lower Limb Spasticity: A Clinical Aspect. Indian J Phy Med Rehab 2020; 31 (4):90-95.
Aims and objectives: The study intended to compare the effect of botulinum toxin A on clinical aspects of spasticity recorded in various scales. It compared the data of upper and lower limb spasticity.
Materials and methods: This is an open-level prospective controlled study, involving patients with upper and lower limb spasticity. Assessment at 3, 12, and 24 weeks post-injections. The modified Ashworth, modified Tardieu scale of spasticity, percentage of passive range motion, Motricity Index for fine and gross motor activity were used. A total of 34 patients were enrolled—25 males, 9 females. There were 51 upper limb and 49 lower limb muscle groups. Three patients were lost after 3 weeks post-baseline follow-up.
Results: There was a significant improvement in all the parametric variables post-injections. Aggregate outcome scores comparing groups post-baseline showed a significant difference in modified Tardieu, Motricity Index, interventional goal assessment scales for lower limb muscle groups from upper limb.
Conclusion: It was concluded that botulinum toxin A has a definite effect on the impairment and focal disability within a rehabilitation setup of selected patients with focal spasticity.
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